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Cialis (tadalafil) is a prescription tablet used for erectile dysfunction and benign prostate hyperplasia. Learn about alternatives, dosage, side effects, and more. What is Cialis? Cialis relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Tadalafil, or generic Cialis, is most commonly used to treat erectile dysfunction (ED). However, it s also used to treat benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension.